From Evidence to Compliance.In days.
AI agents for HEOR, pharmacovigilance, and clinical decision support. Source-grounded. Audit-ready.
ClinicalTrials.gov
EMANICEHAS
Clinical Evidence Retrieval
Medical knowledge now doubles every 73 days. Kirha embeds it in every decision.
Real-time, source-grounded clinical search embedded inside your clinician-facing product. Every answer backed by the latest guidelines, trials, and labels, resolved in the native grammar of each source.
Run where Patient Data must stay
HDS-certified in France. Sovereign cloud, on-prem or your VPC elsewhere.
Clinician query
Kirha · clinical agent
Olaparib, rucaparib, niraparib and talazoparib all sit in the RxNorm PARP-inhibitor class (ATC L01XK). EMA authorises Lynparza monotherapy after new hormonal agents, Akeega (niraparib + abiraterone fixed-dose) for BRCA1/2-mutant mCRPC, and talazoparib + enzalutamide when chemo is not indicated. [1]
PROfound (NEJM 2020): olaparib improved rPFS 7.4 vs. 3.6 mo (HR 0.34) in BRCA1/2/ATM-mutated disease. TALAPRO-2: talazoparib + enzalutamide benefit in the HRR-mutated cohort. FDA mandates a BRCA1/2 companion diagnostic (BRACAnalysis CDx or FoundationOne CDx) before initiation. [2]
Systematic Literature Review
PRISMA 2020-aligned reviews in days, not months.
Two independent screener agents and a judge for conflicts. Dual-reviewer methodology, automated. Queries PubMed, Cochrane, and Epistemonikos by default; bring your own key for Embase, CINAHL, or any source you need.
Aligned with
ICHE2C(R2) · E2D
U.S. Food & Drug AdministrationEMAEuropean Medicines AgencyPharmacovigilance
Safety signals don't wait for your next review cycle.
Kirha agents continuously watch PubMed, EudraVigilance, FAERS, and regional sources, triaged against your product portfolio and pre-assembled into PSUR/PBRER evidence sections, ready for QPPV review.
A workflow that doesn't fit in boxes?
Some problems don't have a name yet. Tell us the recurring task in your clinical or regulatory workflow. We'll tell you if it's automatable.
3500+ clinicians
augmented
Not sure where to start?
Book a 30-minute call. We start from your actual workflow and identify together the highest-value automation opportunity, with no commitment.